Tan F, Lu L, Cai Y, Wang J, Xie Y, Wang L, Gong Y, Xu BE, Wu J, Luo Y, Qiang B, Yuan J, Sun X, Peng X. (2008) Proteomic analysis of ubiquitinated proteins in normal hepatocyte cell line Chang liver cells. Proteomics. 8(14):2885-96

Yu J, Wu J, Francis K, Purchio T and Kadurugamuwa J. Monitoring in vivo fitness of rifampicin resistant Staphylococcus aureus mutants in a mouse biofilm infection model. Journal of Antimicrobial Chemotherapy. 55(4):528-534.(2005)

Jagath Kadurugamuwa J, Modi K, Yu J , Francis K, Purchio T and Contag P. Noninvasive biophotonic imaging of catheter-related urinary tract infection and therapy in living mice. Infection and Immunity. 73(7):3878-3887.(2005)

Jagath Kadurugamuwa, Kshitij Modi, Jun Yu, Kevin Francis, Carlos Orihuela, Elaine Tuomanen, Tony Purchio and Pamela Contag. Noninvasive monitoring of bacterial meningitis and evaluation of drug efficacy in an experimental mouse model. Molecular Imaging. 4(2):137-42. (2005)

Yan Xiong, Julie Willard, Jagath Kadurugamuwa, Jun Yu, Kevin Francis and Arnold Bayer. Real-time in vivo bioluminescent imaging for evaluating the efficacy of antibiotics in a rat Staphylococcus aureus endocarditis model. Antimicrobial Agents and Chemotherapy. 49(1):380-387. (2005)

Sato K, Shikano S, Xia G, Takao J, Chung JS, Cruz PD Jr, Xie XS, Ariizumi K. Selective expression of vacuolar H(+)-ATPase subunit d2 by particular subsets of dendritic cells among leukocytes. Mol Immunol. Sep 3 (2005)

Carlos Orihuela, Geli Gao, Kevin Francis, Jun Yu and Elaine Tuomanen. Tissue-specific contributions of pneumococcal virulence factors to pathogenesis. Journal of Infectious Diseases. 190(9):1661-1669. Cover Story. (2004)

Jagath Kadurugamuwa, Lin Sin, Jun Yu , Kevin Francis, Tony Purchio and Pamela Contag. Noninvasive optical imaging method to evaluate post antibiotic effects on biofilm infection in vivo. Antimicrobial Agents and Chemotherapy. 48(6):2283-2287. (2004)

Xia G, Luo X, Habu T, Rizo J, Matsumoto T, Yu H. Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint. EMBO J. 23(15): 3133-4313. (2004)

Luo X*, Tang Z*, Xia G*, Wassmann K, Matsumoto T, Rizo J, Yu H. The Mad2 spindle checkpoint protein has two distinct natively folded states. Nat Struct Mol Biol. 11(4): 338-45. (2004) [*Equal Author]

Jagath Kadurugamuwa, Lin Sin, Jun Yu, Kevin Francis, Richard Kimura, Tony Purchio and Pamela Contag. Rapid direct method for monitoring antibiotics in a mouse model of bacterial biofilm infection. Antimicrobial Agents and Chemotherapy. 47(10):3130-3137.(2003)

Nelly Kuklin, Gregory Pancari, Timothy Tobery, Leslie Cope, Jesse Jackson, Charles Gill, Karen Overbye, Kevin Francis, Jun Yu, Donna Montgomery, Annaliesa Anderson, William McClements and Kathrin Jansen. Real-time monitoring of bacterial infection in vivo: development of bioluminescent staphylococcal foreign-body and deep-thigh-wound mouse infection models. Antimicrobial Agents and Chemotherapy. 47(9):2740-2748. (2003)

Haesun Park, Kevin Francis, Jun Yu and Patrick Cleary. Membranous cells in nasal-associated lymphoid tissue: a portal of entry for the respiratory mucosal pathogen group A streptococcus. Journal of Immunology. 171(5):2532-2537. Cover Story.(2003)

Jagath Kadurugamuwa J, Sin L, Albert E, Yu L, Francis K,DeBoer M, Rubin M, Bellinger-Kawahara C, Parr Jr T. and Contag P. A direct continuous method to monitor biofilm infection in a mouse model. Infection and Immunity. 71(2):882-890. (2003)

Sun X., Yin, J., Starovasnik, M. A., Fairbrother, W. J., and V. M. Dixit.Identification of a novel homotypic interaction motif required for the phosphorylation of RIP(receptor Interacting Protein) by RIP3 J. BioI. Chern. In press.(2002)

Lu L, Schulz H and Wolf D A. The F-box protein Skp2 mediates androgen control of p27 stability in LNCap human prostate cancer cells. BMC Cell Biology , 3:22 (2002)

Xu, X., Leo, C., Jang, Y., Chan, E., Padilla, D., Huang, BC., Lin T., Gururaja T,Hitoshi Y, Lorens JB, Anderson, D.C., Sikic, B.,Luo Y., Payan, D.G., and Nolan,G.P. Dominant effector genetics in mammalian cells. Nature Genetics 27:23-29(2001)

Yu, P.W., Huang, B., Shen, M., Chan, E., Michael, J., Vue, X., Payan, D.G., and Luo Y.Identification of p15PAF, a novel PCNA associated protein involved in tumor growth. Oncogene 20: 484-489 (2001)

Ma W,XiaC,Ling P,Tan T H,Qiu M,Luo Y,and Liu M.Leukocyte-specific adaptor protein Grap2 interacts with Hematopoietic Progenitor Kinase 1 (HPK1) to activate JNK signaling pathway in T cells. Oncogene 20:1703-1714 (2001)

Holland SJ, Liao XC, Mendenhall MK, Zhou X, Pardo J, Chu P, Spencer C, Fu A,Sheng N, Yu P, Pali E, Nagin A, Shen M, Yu S, Chan E, Wu X, Li C,Woisetschlager M, A versaG, Kolbinger F, Bennett MK, Molineaux S, Luo Y., Payan DG, Mancebo HS, Wu J.Functional Cloning ofSrc-like Adapter Protein-2 (SLAP-2), a Novel Inhibitor of Antigen Receptor Signaling. J. Exp. Merl. 194: 1263-1276 (2001)

Ge, B., Gram, H., Padova, F.D., Huang, B.C., New, L., Ulevitch, R.J., Luo Y., and Han, J.MAP kinase kinase-independent activation ofp38 mediated by TAB I-dependent p38 Autophosphorylation. Science in press (2001)

Holland SH, Liao C, Mendenhall M K, Zhou X, Pardo J, Chu P, Spencer C, Fu CA, Sheng N, Yu P, Pali E, Nagin A, Shen M, Chan E, Wu X, Yu S, Li C, Woisetschlager M, Aversa G, Kolbinger F, Bennett M, Molineaux S, Luo Y, Payan D, Mancebo H SY, and Wu J.. Functional cloning of SLAP-2, a novel inhibitor of antigen-receptor signaling. Journal of Experimental Medicine. 194:1263 (2001).

Elder, M.E., S. Skoda-Smith, T.A. Kadlecek, F. Wang, Wu J., and A. Weiss. Distinct T-cell developmental consequences in humans and mice expressing identical mutations in the DLAARN motif of ZAP-70. Journal of Immunology 166:656. (2001)

Kevin Francis,Jun Yu, Carole Bellinger-Kawahara, Danny Joh, Matthew Hawkinson, Grace Xiao, Anthony Purchio, Michael Caparon, Marc Lipsitch and Pamela Contag. Visualizing pneumococcal infections in the lungs of live mice using bioluminescent Streptococcus pneumoniae transformed with a novel gram-positive lux transposon. Infection and Immunology. 69(5):3350-3358. (2001)

Jun Yu, Alex Bryant, Andrea Marra, Michael Lonetto, David Holmes, David Holden and Damien McDevitt. Characterization of the Streptococcus pneumoniae NADH oxidase that is required for infection. Microbiology. 147(2):431-438. (2001)

Masuda, E.S., Luo Y., Young, C., Shen, M., Rossi, A.B., Huang, B.C., Yu, S.,Payan, D.G., Bennette, M.K., and Scheller, R.H.Rab37 is a novel mast cell specific GTPase localized to secretary granules. FEBS Lett. 470: 61-64 (2000)

Lorens JB, Bennett MK, Pearsall DM, Throndset WR, Rossi AB,Armstrong RJ, Fox BP, Chan EH, Luo Y, Masuda E, Ferrick DA,Anderson DC, Payan DG, and Nolan GP.Retroviral delivery of peptide modulators of cellular functions. Mol. Therapy. I: 438-447 (2000)

Wu J, Cherwinski, Phillips J H, and Lanier L L. DAP10 and DAP12 form distinct, but functionally cooperative, receptor complexes in NK cells. Journal of Experimental Medicine 192:1059. (2000)

Cerwenka A, Bakker A B H, McClanahan T, Wagner J, Wu J, Phillips J H, and Lanier L L. Retinoic acid-early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity 12:721. (2000)

 Paloneva J, Kestila M, Wu J, Salminen A, Bohling T, Ruotsalainen V, Hakola P, Bakker A B H, Phillips J H, Pekkarinen P, Lanier L L,Timonen T, and Peltonen L. Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts. Nature Genetics 25:357. (2000)

Bakker, A.B.H., Wu J., J.H. Phillips, and L.L. Lanier. NK cell activation: distinct stimulatory pathways counterbalancing inhibitory signals. (Review). Human Immunology 61:18. (2000)

Sun X., Lee, J., Navas, T., Baldwin, D., Stewart, T., and V:, M., Dixit. RIP3, a novel Apoptosis-inducing Kinase. J. Bio I. Chern.274: 16871-16875 (1999)

Wu J., Y. Song, A.B.H. Bakker, S. Bauer, T. Spies, L.L. Lanier, and J.H. Phillips. An activating immunoreceptor complex formed by NKG2D and DAP10. Science 285:730. (1999)

Bauer S, Groh V, Wu J, Steinle A,Phillips JH ,Lanier LL, and Spies T.Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285:727. (1999)

L. Lu and R.R. Fiscus. Interleukin-1β causes different levels of nitric oxide-mediated depression of contractility in different positions of rat thoracic aorta. Life Sciences; 64(16):1373-1381. (1999)

L. Lu and R.R. Fiscus. Calcitonin gene-related peptide (CGRP) causes long-term inhibition of contraction in rat thoracic aorta through a nitric oxide-dependent pathway. Neuropeptides; 33(2):145-154. ( 1999)

L. Lu and R.R. Fiscus. NO donors enhance calcitonin gene-related peptide induced elevations of cyclic AMP in vascular smooth muscle cells. European Journal of Pharmacology; 376(3):307-314. ( 1999)

Cho H, Orphanides G, Sun X, Yang X-J, Lees E, Nakatani Y, and Reinberg D.Isolation of a human RNA polymerase II complex containing factors that modify chromatin structure. Mol. Cell. BioI. 18:5355-5363.(1998)

Sun X., Zhang, Y:, Cho, H., Ricket, P., Lees, E., Lane, W., and D., Reinberg.NAT, a human complex containing Srbs polypeptides that functions as a Repressor of activated transcription. Molecular cell 2:213-222.(1998)

Lanier LL, Corliss BC,Wu J, and Phillips JH. Association of DAP12 with activating CD94/NKG2C NK cell receptors. Immunity 8:693. (1998)

Tangye, S.G.,Wu J., G. Aversa, J.E. de Vries, L.L. Lanier, and J.H. Phillips. Negative regulation of human T cell activation by the receptor-type protein tyrosine phosphatase CD148. Journal of Immunology 161:3803. (1998)

Jun Yu and Nick Le Brun. Studies of the cytochrome subunits of menaquinone : cytochrome c reductase (bc complex) of Bacillus subtilis: Evidence for the covalent attachment of heme to the cytochrome b subunit. Journal of Biological Chemistry. 273(15):8860-8866.(1998)

R.R. Fiscus, L. Lu, A.W.K. Tu, H. Hao, L. Yang and X. Wang. Brain natriuretic peptide enhances the endothelium-independent cAMP and vasorelaxant responses of calcitonin gene-related peptide in rat aorta. Neuropeptides; 32(6):499-509. (1998)

Wu J., Q. Zhao, T. Kurosaki, and A. Weiss. The Vav binding site (Y315) in ZAT-70 is critical for antigen receptor-mediated signal transduction. Journal of Experimental Medicine 185:1877. (1997)

Wu J., D.G. Motto, G.A. Koretzky, and A. Weiss. Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation. Immunity 4:503. (1996)

Tang, H#, Sun X., Reinberg, D., and R., Ebright.Protein-protein interactions in eukaryotic transcription initiation: Structure of the preinitiation I complex.Proc. Natl. Sci. USA Vol 93:1119-1124 #: equal contribution(1996)

Motto, D.G., S.E. Ross,Wu J., K. Hendricks-Taylor, and G.A Koretzky. Implication of the Grb2-associated phosphoprotein SLP-76 in TCR-mediated IL-2 production. Journal of Experimental Medicine 183:1937. (1996)

Wu J., S. Katzav, and A. Weiss. A functional T-cell receptor signaling pathway is required for p95vav activity. Molecular and Cell.ular Biology 5:4337. (1995)

Jun Yu, Lars Hederstedt and Patrick Piggot. The cytochrome bc complex (menaquinone:cytochrome c reductase) in Bacillus subtilis has a non-traditional subunit organization. Journal of Bacteriology. 177(23):6751-6760.(1995)

Sun X., Ma, D., Sheldon, M., Yeung, K., and D., Reinberg.Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription.Genes & Development 8:2236-2348(1994)

Ma, D., Watanabe, H., Mermelstein, F., Admon, A., Oguri, K., Sun X., Wada, T., lmai, T.,Shiroya, T., Reinberg, D., and H., Handa. Isolation of a cDNA encoding the largest subunit of TFlIA reveals functions important for activated transcription. Genes & Development 7:2246-2257(1993)

Ha,I., Boberts,S., Maldonado,E., Sun X., Kim L., Green, M., and D., Reinberg.Multiple functional domains of human transcription factor 1m: distinct interactions with two general transcription factors and RNA polymerase II. Genes & Development 7:1021-1032(1993)

Wu J., M.A. Palladino, I.S. Figari, and R.E. Morris. Comparative immunoregulatory effects of Rapamycin, FK506 and Cyclosporine on mitogen--induced cytokine production and lymphoproliferation. Transplantation Procedings 23: 238. (1991)

Morris, R.E., B.M. Meiser, Wu J., R. Shorthouse and J. Wang. Use of Rapamycin for the suppression of alloimmune reactions in vivo: schedule dependence, tolerance induction, synergy with Cyclosporine and FK506, and effects on host-versus-graft and graft-versus- host reactions. Transplantation Procedings 23: 521. (1991)

Jun Yu, Lingfang Wang, Shiying Miao and Yuanchang Yan. Anti-idiotypic antibody related to the 84 kD human sperm membrane protein. Cell Research. 1(2):163-172.(1990)

Morris, R E, Wu J, and R Shorthouse. A study of the contrasting effects of Cyclosporine, FK506, and Rapamycin on the suppression of allograft rejection. Transplantation Procedings 22:1638. (1990)

Morris, R.E., Wu J., and R. Shorthouse. Comparative immunopharmacologic effects of FK506 and CyA in in vivo models of organ transplantation. Transplantation Procedings 22:110. (1990)

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